Pediatric Neuro-oncology Cell Atlas
Pediatric Neuro-oncology Cell Atlas
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A survey of childhood Ependymoma
scRNA-seq of 26 childhood ependymoma samples
UCSC Cell Browser
GEO dataset
Manuscript
Single-cell RNA-seq of childhood medulloblastoma
scRNA-seq of 28 childhood medulloblastoma samples
UCSC Cell Browser
GEO dataset
Publication
Preprint
Analysis Code
Spatial transcriptomic analysis of the ependymoma tumor microenvironment
Spatial transcriptomics of posterior fossa subgroup A (PFA) Ependymoma
Publication
GEO dataset
Shiny App
Preprint
Single-nuclei RNA-seq of childhood PFA Ependymoma recurrence
snRNA-seq of 7 matched primary and first recurrence childhood EPN PFA samples
UCSC Cell Browser
GEO dataset
Manuscript
Characterizing the immunobiology of high risk pediatric ependymoma
Multi-Omic approach identifies hypoxic tumor-associated myeloid cells that drive immunobiology of high risk pediatric ependymoma
UCSC Cell Browser
Publication
Multi-pronged analysis of pediatric low-grade glioma reveals a unique tumor microenvironment associated with BRAF alterations
scRNA-seq of 23 pediatric low-grade glioma (pLGG) patient samples
UCSC Cell Browser
Integration of single-nuclei RNA-sequencing and spatial transcriptomics defines the complex microenvironment of NF1-associated plexiform neurofibromas
single nuclei RNA-seq and spatial transcriptomics of plexiform neurofibromas
UCSC Cell Browser
GEO dataset
Publication
Single-cell RNA-seq of pediatric high-grade glioma
scRNA-seq of 19 pediatric high-grade glioma (PHGG) patient samples
UCSC Cell Browser
Publication
GEO dataset
Publications
John DeSisto
,
Andrew M Donson
,
Andrea M Griesinger
,
Rui Fu
,
Kent Riemondy
,
Jean Mulcahy Levy
,
Julie A Siegenthaler
,
Nicholas K Foreman
,
Rajeev Vibhakar
,
Adam L Green
(2023).
Tumor and immune cell types interact to produce heterogeneous phenotypes of pediatric high grade glioma
.
Neuro. Oncol.
.
PDF
Cite
DOI
Vladimir Amani
,
Kent A Riemondy
,
Rui Fu
,
Andrea M Griesinger
,
Enrique Grimaldo
,
Graziella Ribeiro De Sousa
,
Ahmed Gilani
,
Molly Hemenway
,
Nicholas K Foreman
,
Andrew M Donson
,
Nicholas Willard
(2023).
Integration of single-nuclei RNA-sequencing, spatial transcriptomics and histochemistry defines the complex microenvironment of NF1-associated plexiform neurofibromas
.
Acta Neuropathol Commun
.
Cite
DOI
URL
Andrea M Griesinger
,
Kent Riemondy
,
Nithyashri Eswaran
,
Andrew M Donson
,
Nicholas Willard
,
Eric W Prince
,
Simon M L Paine
,
Georgia Bowes
,
John Rheaume
,
Rebecca J Chapman
,
Judith Ramage
,
Andrew Jackson
,
Richard G Grundy
,
Nicholas K Foreman
,
Timothy A Ritzmann
(2023).
Multi-Omic approach identifies hypoxic tumor-associated myeloid cells that drive immunobiology of high risk pediatric ependymoma
.
iScience
.
Cite
DOI
URL
Andrew M Donson
,
Kelsey C Bertrand
,
Kent A Riemondy
,
Dexiang Gao
,
Yonghua Zhuang
,
Bridget Sanford
,
Gregory A Norris
,
Rebecca J Chapman
,
Rui Fu
,
Nicholas Willard
,
Andrea M Griesinger
,
Graziella Ribeiro De Sousa
,
Vladimir Amani
,
Enrique Grimaldo
,
Todd C Hankinson
,
Ffyona Booker
,
Martin Sill
,
Richard G Grundy
,
Kristian W Pajtler
,
David W Ellison
,
Nicholas K Foreman
,
Timothy A Ritzmann
(2023).
Significant increase of high-risk chromosome 1q gain and 6q loss at recurrence in posterior fossa group A ependymoma: a multicenter study
.
Neuro. Oncol.
.
Cite
DOI
URL
Rui Fu
,
Gregory A Norris
,
Nicholas Willard
,
Andrea M Griesinger
,
Kent A Riemondy
,
Vladimir Amani
,
Enrique Grimaldo
,
Faith Harris
,
Todd C Hankinson
,
Siddhartha Mitra
,
Timothy A Ritzmann
,
Richard R Grundy
,
Nicholas K Foreman
,
Andrew M Donson
(2022).
Spatial transcriptomic analysis delineates epithelial and mesenchymal subpopulations and transition stages in childhood ependymoma
.
Neuro. Oncol.
.
Cite
DOI
URL
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Contact
andrew.donson@cuanschutz.edu
Dept of Pediatrics and The Morgan Adams Foundation Pediatric Brain Tumor Research Program, Aurora, CO 80045
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